Diagnostic challenges of nonalcoholic fatty liver disease/nonalcoholic steatohepatitis
نویسندگان
چکیده
منابع مشابه
Nonalcoholic Steatohepatitis: Diagnostic Challenges.
This article reviews diagnostic criteria for nonalcoholic steatohepatitis (NASH), current grading and staging methodology, and diagnostic challenges and pitfalls in routine practice. Current practice guidelines and prognostic and treatment considerations are discussed. The clinical diagnosis of nonalcoholic fatty liver disease may represent stable disease without progressive liver damage, in th...
متن کاملFatty Liver and Nonalcoholic Steatohepatitis
Background: Fatty liver (FL) is the most common liver disease but its clinical significance remains elusive. Nonalcoholic steatohepatitis (NASH) is increasingly recognized as a cause of liver failure, sometimes recurring following transplantation. Recent data on both conditions are critically reviewed. Methods: A Medline search of the medical literature (1990 to September 1998) and cross-refere...
متن کاملNonalcoholic fatty liver disease and nonalcoholic steatohepatitis.
Nonalcoholic fatty liver disease (NAFLD) is a well-recognized form of chronic liver disease affecting both children and adults that has gained increased recognition. Recently NAFLD has been associated with insulin resistance and its incidence and prevalence is likely increasing, paralleling the rise in obesity and diabetes mellitus in the United States. The article includes current thoughts on ...
متن کاملRodent Models of Nonalcoholic Fatty Liver Disease/Nonalcoholic Steatohepatitis
Research in nonalcoholic fatty liver disease (NAFLD), including nonalcoholic steatohepatitis (NASH), has been limited by the availability of suitable models for this disease. A number of rodent models have been described in which the relevant liver pathology develops in an appropriate metabolic context. These models are promising tools for researchers investigating one of the key issues of NASH...
متن کاملMurine Models of Nonalcoholic Fatty Liver Disease and Steatohepatitis
In 1980, Ludwig et al. first reported patients of steatohepatitis who lacked a history of excessive alcohol consumption but showed liver histology resembling alcoholic hepatitis and progression to cirrhosis of the liver accompanied by inflammation and fibrosis. The development of nonalcoholic steatohepatitis (NASH) is associated with obesity, diabetes mellitus, insulin resistance, and hyperlipi...
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ژورنال
عنوان ژورنال: Clinical Liver Disease
سال: 2018
ISSN: 2046-2484
DOI: 10.1002/cld.716